NifedipineExtended-release Tablets, USP30 mg, 60 mg and 90 mg

ثبت نشده
چکیده

Nifedipine Extended-release Tablet depends for its action on the existence of an osmotic gradient between the contents of the tablet core and fluid in the GI tract. Drug delivery is essentially constant as long as the osmotic gradient remains constant, and then gradually falls to zero. Upon swallowing, the biologically inert components of the tablet remain intact during GI transit and are eliminated in the feces as an insoluble shell.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Formulation of Extended-Release Gliclazide Tablet Using a Mathematical Model for Estimation of Hypromellose

Formulation of gliclazide in the form of extendedrelease tablet in 30 and 60 mg dosage forms was performed using hypromellose (HPMC K4M) as a retarding agent. Drug-release profiles were investigated in comparison with references Diamicron MR 30 and 60 mg tablets. The effect of size of powder particles, the amount of hypromellose in formulation, hardness of tablets, and also the effect of halvin...

متن کامل

In Vitro Release Studies of Enoxaparin in Nanoparticle form and Enterically Coated Tablets Containing Surfactants

In the past decade, many strategies have been developed to enhance oral drug delivery. Different techniques were investigated, amongst those the use of permeation enhancers such surfactants and biodegradable polymers were studied more extensively. Chitosan and its derivatives have been studied as permeation enhancer. The aim of the current study was to develop a nanoparticulate system based on ...

متن کامل

Formulation, release and stability study of Bupropion sustained release 150 mg using Hydroxypropylmethylcellulose (HPMC) 4000cps basis

In this study,formulation of sustained-releasingmatrix tablet of bupropion 150 mg, using hydroxypropylmethylcellu lose(HPMC) 4000cps was evaluatedwith the aim of reducing the frequency of daily dose. The level of HPMC4000 ,polyvinylpyrolidone(PVP) and magnesium stearate(Mg St)was varied based on a 2level 3 factor factorial experimental designusing the release rate of the drug from the matrices ...

متن کامل

Preparation, Characterization and in vitro Release Studies of Enoxaparin in Nanoparticle form and Enterically Coated Tablets Containing Different Enhancers

In the past decade, many strategies have been developed to enhance oral drug delivery. Different techniques were investigated, amongst those the use of permeation enhancers such surfactants and biodegradable polymers were studied more extensively. Chitosan derivatives have been studied as permeation enhancer in free soluble form and as nanoparticulate systems. The aim of the current work wa...

متن کامل

Formulation and in Vitro Evaluation of Aspirin and Isosorbide 5-mono- Nitrate Sustained Bilayer Tablets

In this study, aspirin (AS) and isosorbide 5mononitrate(ISM) sustained bilayer tablets were developed by wet granulation and compression technique, the influence of the contents of PVPP on the dissolution of AS from the tablets was investigated. An orthogonal experiment design was used to optimize ISM sustained release layer. The tablets were tested for their drug content, hardness, thickness, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016